Chloroform SOP

Chemical Name: CAS #:
Hazard Classification:
Location Used: Principal Investigator:
Processes for Which Chemical Is Used:
HAZARDS AND PROTECTION
Hazard Information
• Carcinogen
• Reproductive Toxicity
• Liver and Kidney Toxicity
Routes of Exposure
• Ingestion ● Skin Absorption
• Inhalation
• Eye absorption
If exposed by:
• Inhalation: Remove to fresh air
• Ingestion: Aspiration hazard if vomiting
occurs. Do not induce vomiting.
• Eye or skin: Rinse affected area for 15
minutes
If exposed by inhalation, ingestion or eye contact, seek
medical attention. For other routes, seek medical
attention if necessary.
Symptoms of Exposure
• Cough, shortness of breath, dizziness,
agitation, inebriation, nausea, vomiting
• Headache, drying out of skin
Exposure Limits
All exposure limits are Time Weighted Averages
(average exposure over an eight-hour day) unless
otherwise indicated.
OSHA PEL: 50 ppm (240 mg/m3
) ceiling
ACGIH TLV: 10 ppm (48 mg/m3
)
NIOSH REL: 2 ppm (9.5 mg/m3
)
Engineering Controls
• Chemical Fume Hood Never open chloroform outside of a chemical fume
hood.
Administrative Controls
• Designated area sign
• Particularly hazardous substance label
• Post designated area sign before each use.
• Label containers of chloroform as a health
hazard.
• Use as small a quantity as possible.
Chloroform 67-66-3
Health Hazard
ARKANSAS STATE UNIVERSITY EHS
LABORATORY CHEMICAL STANDARD OPERATING PROCEDURE
CS-002 Last Reviewed August 16, 2018
Personal Protective Equipment
• Gloves
• Safety glasses or splash goggles
• Lab coat
Two pairs of nitrile gloves for short-term use. If longer
term use, polyvinyl alcohol (PVA) or laminate gloves
are required. Change gloves immediately if a spill on
gloves is observed. Wash hands after use.
OTHER SAFETY INFORMATION
Transportation Follow guidance given in the laboratory safety manual
for transport of chemicals.
Storage
• Can be stored with flammable materials
(except acetone).
• Keep tightly sealed
Incompatible materials include:
Acetone, strong bases, alkali metals, fluorine,
dinitrogen tetroxide, potassium t-butoxide, powdered
aluminum, nitrogen tetroxide, powdered magnesium,
disilane, sodium methylate, triisopropylphosphine.
Spill/Accident Procedures
For all spills:
• Wear two pairs of nitrile gloves
• Evacuate the immediate area
Exposure:
• If anyone exposed requires emergency
medical attention, dial 911 (or 9-911 from
landline).
• Follow procedures outlined in laboratory
safety manual.
Small spills (less than 500 mL in a hood or 20 mL
outside a fume hood): Cover the spill with absorbent
materials. Place absorbent materials in bag or bucket
for collection by EHS. Clean area with soap and water
once spill is removed.
Large spills (greater than 500 mL in a hood or 20 mL
outside a fume hood): If the spill is in a chemical fume
hood, contact the EHS director (864-710-2933). If he
cannot be reached (does not answer phone, do not
leave voicemail), then call 911, pull the fire alarm and
exit the building. If the spill is outside of a hood, then
call 911, pull the fire alarm and exit the building.
Waste Disposal Waste chloroform must be collected for disposal.
Empty bottles of chloroform may be rinsed and
thrown in the dumpster.
By signing below, you indicate that you have reviewed this SOP and understand the contents thereof:
Printed Name Signature Date
ARKANSAS STATE UNIVERSITY EHS
LABORATORY CHEMICAL STANDARD OPERATING PROCEDURE
CS-002 Last Reviewed